Category: Antigen Screening
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Case Study: Identification of a McLeod phenotype blood donor
Background/Case Studies: The McLeod phenotype is defined as the absence of the Kx antigen from the red blood cell (RBC) membrane. Kx is the only antigen in the XK blood group system. The Kx antigen is located on the Xk protein, which is linked to the KEL glycoprotein by a single disulfide bond. Absence of the…
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How to Investigate those Pesky Serologic Weak D Samples
When typing a patient for the RhD antigen, hospitals have been forced to convert a non-binary result into a positive or negative for purposes of entry into the electronic health record as well as for selection of blood products including Rh immune globulin (RhIG). RhD is not unique amongst blood group antigens in demonstrating a…