Category: Neonatal and Pediatric
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Multi-institution study of group O blood usage in the pediatric population between 2015 and 2019
Introduction Information and guidance for transfusion of pediatric and neonatal patients remained unchanged between the 2019 and 2025 versions of the AABB Association Bulletin “Recommendations on the Use of Group O Red Blood Cells.”1,2 The bulletin acknowledged the ease of using group O red blood cells (RBCs) for neonates since one RBC unit could provide…
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Biotin-labeled red cell survival in pediatric patients with sickle cell disease who form antibodies of uncertain clinical significance
Patients of all ages with sickle cell disease (SCD) who are frequently transfused develop more auto- and alloantibodies against RBC antigens compared to the general population of transfused patients.[1] [2] In addition, chronically transfused children, compared to those who are infrequently transfused, are over three times more likely to develop warm autoantibodies (WAA),[3] which are…
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REDy, Set, Go – the REDS-IV-P Program
In the United States, and globally, the “REDS” moniker is well-known and widely regarded in the transfusion medicine community. Funded by the US National Heart, Lung and Blood Institute of NIH, the original REDS program (initiated in 1989 and renewed through 2001) stood for Retrovirus Epidemiology Donor Study and was introduced to address concerns for HIV and…