Tag: HBOCs
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Hemoglobin-Based Oxygen Carriers – Are We There Yet?
Jahr and colleagues1 recently summarized the history of hemoglobin-based oxygen carriers (HBOCs) to the present day, comparing biochemical and biophysical properties, safety concerns, and therapeutic potential as alternatives to packed red blood cell (PRBC) transfusions. HBOCs have been investigated for nearly a century as synthetic oxygen carriers in situations including the unavailability of rare antigen-negative…